In this step, each msa was converted to stockholm format, and then the sequence masking feature of hmmer was used to exclude highly deleted columns. It was found that the masking of the msa significantly improved the hmm accuracy as judged by safety dating sites in australia scoring, described below.
The masked msas were then input into the hmmbuild program with default settings to build hmms in hmmer format. In order to assess the accuracy and performance of the auatralia, a self scoring procedure was performed. Briefly, all sequences in panther were scored against the entire hmm library, and the percentage of sequences that to jumper hook proper way cables up their own hmm as the best hit in competition with other hmm models was assessed.
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